Tuesday, June 21, 2011

Early Detection of Colorectal Cancer

Patients with colorectal cancer can be cured if the malignancy is detected early. Conventional tests such as blood tests and digital rectal cryptic, but cancer can be detected at an advanced stage. Now, studies led technique that can detect this cancer early.
Colorectal cancer (CRC) is a malignant disease that occurs in the colon to the rectum. The time is slow growing cancer, 15-20 years old.
"When detected early, recovering patients very big opportunity," said the expert in hematology oncology at the Medical Faculty of the University of Indonesia (Faculty of Medicine), Aru W Sudoyo, collecting from patients with colorectal cancer in Jakarta, Saturday (14 / 5) .
 
According to him, so much as 95 percent of cases are treated for colon cancer, if detected early has to be through testing and detailed inspection. Unfortunately, this has not happened in Indonesia. The majority of patients diagnosed with colon cancer for treatment if they had advanced. More than 50 percent of cancer patients are unconscious and found too late disease.
According to Ibrahim Basir, abdominal surgeon at the Faculty of Medicine, there are early signs of recognizing the early stages of colon cancer, may be accompanied by other weight loss through a change in bowel changes or bloody stools.
Other symptoms of diarrhea or constipation without apparent cause for more than six weeks, pain in the back of the abdomen, bloating, stomach felt or even still full after defecation.
"Most people felt the symptoms were reluctant to seek medical attention. She also wants digital rectal examination is not a disgrace," he said.
In fact, the easiest way to diagnose cancer, colon cancer.
Early
Digital rectal examination is performed to spend the presence of polyps in the hole at the same time to determine abnormalities in the prostate to determine. Occult blood tests in the laboratory in patient stool samples performed to detect the presence of blood that comes from polyps.
Two ways it can contribute to a picture of better treatments and effective. In addition to non-invasively, from observation of the colon (colonoscopy) performed two-introducing a different way, namely biomolecular detection and radioisotope examination with barium.
Barium enema test, liquid barium into the intestine brought through the rectum and then detected by X-rays. This examination can detect cancer and polyps in the amount of more than 1 cm.
Biomolecular recently for colorectal cancer in stool samples of patients introduced to test tumor M2-PK (pyruvate kinase M2), which is a marker (biomarker) is metabolic tumors.
The marker gene Eigenbrodt E is found in Germany was in 1992, then developed ScheBo Biotech. In the study measured the metabolic activity of colon cancer at an early stage.
"This method can be adenomas or polyps that bleed do not know," said Adityawati Ganggaiswari, biomedical experts from Indonesia Cancer Foundation.
DNA testing clinics opened in Lebak Bulus yki, Jakarta. Rate of Rp 200,000. Investigation of the M2-PK in stool samples of patients in a laboratory owned by Kalbe Farma will be carried out, said Adityawati.
Yki In addition, there are two hospitals in Jakarta, which provides the service.
In the world, colon cancer, resulting in the deaths of about 608,000. This represents 8 percent of all cancer deaths and the fourth type of cancer that causes death. Nearly 60 percent of cases are found in developing countries, including Indonesia.
Relation to nutrition
In Indonesia, Handoko Santoso, Director of Medical and Regulatory Sanofi-Aventis Group, said in Indonesia, even in young people at high risk for colon cancer. In fact, it was found in children of 13 years.
"It is closely associated with changes in diet and lifestyle are the west, especially in urban areas in the context," said Aru.
Way and the wrong diet is not healthy, it's eating too many foods high in fat and low in fiber are often preservatives and dyes that are not exposed to food. In addition, the lifestyle is at the risk of colorectal cancer is smoking, less exercise, and many sit / lack of exercise.
For the suppression of colorectal cancer cases in developed countries including the United States issued regulations require that these over 50 years with an endoscopy-based detection, such as colonoscopy in the elderly. This method can be found without symptoms of colorectal cancer

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